PYRROLOPYRAZINE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS
摘要
The invention relates to pyrrolopyrazine-spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
申请公布号
EP3056495(A1)
申请公布日期
2016.08.17
申请号
EP20150196033
申请日期
2012.02.02
申请人
VERTEX PHARMACEUTICALS INC.
发明人
HADDIDA RUAH, SARA S.;KALLEL, EDWARD ADAM;MILLER, MARK THOMAS;ARUMUGAM, VIJAYALAKSMI;MCCARTNEY, JASON;ANDERSON, COREY;GROOTENHUIZEN, PETER DIEDERIK JAN;JIANG, LICONG