发明名称 |
USE OF INACTIVATED JAPANESE ENCEPHALITIS VIRUS PARTICLE AS ADJUVANT |
摘要 |
A method for using inactivated Japanese encephalitis virus particles as an adjuvant of a vaccine is provided. A method for using inactivated Japanese encephalitis virus (JEV) particles as an adjuvant of various vaccines or a mixed vaccine, said JEW particles being obtained by inoculating JEV Beijing-1 strain to Vero cells, culturing said JEV-infected cells to give cultured cells or culture supernatant, purifying JEV particles from said cultured cells or culture supernatant and inactivating said JEV particles with formalin, a method for preparing a (mixed) vaccine which comprises a step of letting inactivated Japanese encephalitis virus be contained, and a mixed vaccine prepared by said method. |
申请公布号 |
EP2298344(B1) |
申请公布日期 |
2016.08.17 |
申请号 |
EP20090758247 |
申请日期 |
2009.05.27 |
申请人 |
THE CHEMO-SERO-THERAPEUTIC RESEARCH INSTITUTE |
发明人 |
MORIYAMA, MAKOTO;KAMINAKA, KAZUYOSHI;MATSUDA, JUNICHI;NOZAKI, CHIKATERU |
分类号 |
A61K39/00;A61K39/39;A61P31/14 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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