| 摘要 |
Provided is a simple, safe, and industrially practical method for producing a pentafluorosulfanylbenzoic acid. This method includes (A) a providing step of providing a trihalomethyl(pentafluorosulfanylbenzene) represented by general formula (1):
where X is a halogen atom, n is an integer of 1 ‰¤ n ‰¤ 3, and the hydrogen atoms on the benzene ring are optionally replaced with a group having an oxygen atom, a group having a nitrogen atom, or a halogen atom;
(B1) a step of reacting the trihalomethyl(pentafluorosulfanylbenzene) with a carboxylic acid, water, or a disiloxane represented by general formula (b):
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒR 3 Si-O-SiR 3 €ƒ€ƒ€ƒ€ƒ€ƒ(b)
(where R 3 is an alkyl group)
in the presence of an acid other than carboxylic acids to form a pentafluorosulfanylbenzoic halide represented by general formula (2a):
where X and n are as defined above, and the hydrogen atoms on the benzene ring are optionally replaced with the group or atom defined above; and
(B2) a step of converting the pentafluorosulfanylbenzoic halide into a pentafluorosulfanylbenzoic acid represented by general formula (2):
where n is as defined above, and the hydrogen atoms on the benzene ring are optionally replaced with the group or atom defined above. |
