发明名称 SELECTIVE ANTISENSE COMPOUNDS AND USES THEREOF
摘要 The present disclosure provides oligomeric compounds. Certain such oligomeric compounds are useful for hybridizing to a complementary nucleic acid, including but not limited, to nucleic acids in a cell. In certain embodiments, hybridization results in modulation of the amount activity or expression of the target nucleic acid in a cell. In certain embodiments, certain oligomeric compounds selectively reduce the expression of a target nucleic acid transcript relative to a non-target nucleic acid transcript.
申请公布号 EP2951304(A4) 申请公布日期 2016.08.10
申请号 EP20140746305 申请日期 2014.02.04
申请人 IONIS PHARMACEUTICALS, INC. 发明人 OESTERGAARD, MICHAEL;SETH, PUNIT, P.;SWAYZE, ERIC, E.
分类号 C07H21/00;A61K48/00;C12N15/11 主分类号 C07H21/00
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