发明名称 |
SELECTIVE ANTISENSE COMPOUNDS AND USES THEREOF |
摘要 |
The present disclosure provides oligomeric compounds. Certain such oligomeric compounds are useful for hybridizing to a complementary nucleic acid, including but not limited, to nucleic acids in a cell. In certain embodiments, hybridization results in modulation of the amount activity or expression of the target nucleic acid in a cell. In certain embodiments, certain oligomeric compounds selectively reduce the expression of a target nucleic acid transcript relative to a non-target nucleic acid transcript. |
申请公布号 |
EP2951304(A4) |
申请公布日期 |
2016.08.10 |
申请号 |
EP20140746305 |
申请日期 |
2014.02.04 |
申请人 |
IONIS PHARMACEUTICALS, INC. |
发明人 |
OESTERGAARD, MICHAEL;SETH, PUNIT, P.;SWAYZE, ERIC, E. |
分类号 |
C07H21/00;A61K48/00;C12N15/11 |
主分类号 |
C07H21/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|