| 发明名称 |
SLOW-RELEASE CONJUGATES OF SN-38 |
| 摘要 |
Conjugates of SN-38 that provide optimal drug release rates and minimize the formation of the corresponding glucuronate are described. The conjugates release SN-38 from a polyethylene glycol through a β-elimination mechanism. |
| 申请公布号 |
EP3052101(A1) |
申请公布日期 |
2016.08.10 |
| 申请号 |
EP20140796322 |
申请日期 |
2014.10.03 |
| 申请人 |
PROLYNX LLC |
发明人 |
ASHLEY, GARY;SCHNEIDER, ERIC L. |
| 分类号 |
A61K31/4745;A61K9/00;A61K35/00;A61K47/10;A61K47/20;A61K47/48;C07D457/00;C08G83/00 |
主分类号 |
A61K31/4745 |
| 代理机构 |
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