发明名称 |
SELECTIVE ANTISENSE COMPOUNDS AND USES THEREOF |
摘要 |
The present invention provides oligomeric compounds. Certain such oligomeric compounds are useful for hybridizing to a complementary nucleic acid, including but not limited, to nucleic acids in a cell. In certain embodiments, hybridization results in modulation of the amount, activity, or expression of the target nucleic acid in a cell. In certain embodiments, hybridization results in selective modulation of the amount, activity, or expression of a target Huntingtin gene or Huntingtin transcript in a cell. |
申请公布号 |
EP2906256(A4) |
申请公布日期 |
2016.08.10 |
申请号 |
EP20130845550 |
申请日期 |
2013.10.11 |
申请人 |
IONIS PHARMACEUTICALS, INC. |
发明人 |
OESTERGAARD, MICHAEL;SETH, PUNIT, P.;SWAYZE, ERIC, E. |
分类号 |
A61K31/7125;C12N15/113 |
主分类号 |
A61K31/7125 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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