发明名称 |
JOINT FAT PAD FORMULATIONS, AND METHODS OF USE THEREOF |
摘要 |
The present invention relates to formulations for administration to a joint fat pad of a subject, and to methods of treating joint pain, inflammation or disease. The disclosed formulations are intended for local administration to the joint fat pad to provide sustained release of a therapeutic agent to the joint cavity and surrounding tissues. The joint may be an arthritic joint, an injured joint or a surgically replaced joint. The therapeutic agent may be an analgesic agent, an anti-inflammatory agent or an immunosuppressive agent. A single administration of the formulation to the joint fat pad delivers a therapeutically effective amount of the therapeutic agent with reduced systemic exposure relative to a single systemic or a single intra-articular administration of a therapeutic dose of an identical therapeutic agent. |
申请公布号 |
WO2016123352(A1) |
申请公布日期 |
2016.08.04 |
申请号 |
WO2016US15384 |
申请日期 |
2016.01.28 |
申请人 |
ALLERGAN, INC. |
发明人 |
JIANG, GUANG-LIANG;TURKEL, CATHERINE C.;STERN, MICHAEL;SCHAUMBURG, CHRISTOPHER S.;BLANDA, WENDY |
分类号 |
A61L31/04;A61L31/14;A61L31/16 |
主分类号 |
A61L31/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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