发明名称 |
BIOMARKER |
摘要 |
The invention relates to methods of treating chronic intestinal inflammation and/or inflammatory bowel disease by administering an antagonist of oncostatin-M (OSM) and/or OSM receptor-β (OSMR). The invention also relates to methods for diagnosing or prognosing chronic intestinal inflammation and/or inflammatory bowel disease in an individual and for predicting whether or not an individual will respond to an anti-TNFα therapy. The methods comprise measuring OSM and/or OSMR in the individual. |
申请公布号 |
WO2016120625(A1) |
申请公布日期 |
2016.08.04 |
申请号 |
WO2016GB50185 |
申请日期 |
2016.01.28 |
申请人 |
ISIS INNOVATION LIMITED |
发明人 |
WEST, NATHANIEL RICHARD;OWENS, BENJAMIN MICHAEL JOSEPH;HEGAZY, AHMED NABIL;POWRIE, FIONA MARGARET |
分类号 |
C07K16/24;A61P1/00;A61P37/06 |
主分类号 |
C07K16/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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