发明名称 |
CULTURE METHOD RELATED TO DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO BLOOD CELLS |
摘要 |
It is an object of the present invention to provide a method for efficient differentiation into blood cells. Specifically, in the present invention, when blood cells are produced from pluripotent stem cells such as ES cells or iPS cells in vitro, the cells are cultured under a low oxygen partial pressure to increase the efficiency of differentiating the pluripotent stem cells into hematopoietic progenitor cells, erythroid progenitor cells, and the like, so as to increase the number of finally obtained, desired blood cells. |
申请公布号 |
EP2615165(B1) |
申请公布日期 |
2016.08.03 |
申请号 |
EP20110823660 |
申请日期 |
2011.09.09 |
申请人 |
THE UNIVERSITY OF TOKYO;TERUMO KABUSHIKI KAISHA |
发明人 |
SANO, SHINYA;ETO, KOJI;TAKAYAMA, NAOYA;NAKAUCHI, HIROMITSU |
分类号 |
C12N5/00;A61K35/12;A61K35/14;A61K35/18;A61P7/00;A61P7/08;C12N5/078;C12N5/0789;C12Q1/06 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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