发明名称 |
METHODS FOR TREATING HEMATOLOGIC CANCERS |
摘要 |
The present invention relates to methods of treating hematologic cancers using a combination of inhibitors of PD-1 or PD-L1 and TIM-3, LAG-3 or CTLA-4. In one embodiment, an inhibitor of PD-1 or PD-L1 is administered in combination with an inhibitor of TIM-3. In another embodiment, an inhibitor of PD-1 or PD-L1 is administered in combination with an inhibitor of LAG-3. In yet another embodiment, an inhibitor of PD-1 or PD-L1 is administered in combination with an inhibitor of CTLA-4. |
申请公布号 |
EP3049442(A1) |
申请公布日期 |
2016.08.03 |
申请号 |
EP20140848888 |
申请日期 |
2014.09.25 |
申请人 |
COSTIM PHARMACEUTICALS INC.;THE MEDICAL COLLEGE OF WISCONSIN, INC. |
发明人 |
JOHNSON, BRYON, DUANE;MILLMAN, ROBERT |
分类号 |
C07K16/28;A61K39/395;A61N5/00 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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