| 发明名称 |
RECOMBINANT P.FALCIPARUM MEROZOITE PROTEIN-1 42 VACCINE |
| 摘要 |
In this application is described the expression and purification of a recombinant Plasmodium falciparum (FVO) MSP-1<SUB>42</SUB>. The method of the present invention produces a highly purified protein that retains folding and disulfide bridging of the native molecule. The recombinant MSP-1<SUB>42 </SUB>is useful as a diagnostic reagent, for use in antibody production, and as a vaccine. |
| 申请公布号 |
EP1497307(B1) |
申请公布日期 |
2016.08.03 |
| 申请号 |
EP20030726193 |
申请日期 |
2003.04.01 |
| 申请人 |
WALTER REED ARMY INSTITUTE OF RESEARCH |
发明人 |
ANGOV, EVELINA;LYON, JEFFERY, A.;DARKO, CHRISTIAN, ASARE;COHEN, JOE, D. |
| 分类号 |
C07H21/04;A61K39/00;C07H21/02;C07K14/445;C12N1/21;C12N15/00;C12N15/30;C12N15/67;C12P21/02;C12P21/04;C12P21/06 |
主分类号 |
C07H21/04 |
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