The present disclosure provides oligomeric compounds. Certain such oligomeric compounds are useful for hybridizing to a complementary nucleic acid, including but not limited, to nucleic acids in a cell. In certain embodiments, hybridization results in modulation of the amount activity or expression of the target nucleic acid in a cell.
申请公布号
EP2906255(A4)
申请公布日期
2016.07.27
申请号
EP20130844964
申请日期
2013.10.11
申请人
IONIS PHARMACEUTICALS, INC.
发明人
KORDASIEWICZ, HOLLY;MAZUR, CURT;SETH, PUNIT, P.;SWAYZE, ERIC, E.