| 摘要 |
Acetylpropyl chloride is produced by reacting acetylbutyrolactone with aqueous hydrochloric acid in substantially mol. for mol. proportions at the boiling point of the mixture, withdrawing and condensing the vapour, and separating the acetylpropyl chloride from the condensate. In an example, aqueous hydrochloric acid and acetylbutyrolactone are placed in a flask fitted with a two-plate bubble cap fractionating column, condenser, separator and seal to permit continuous return of the water layer from the separator to the column. The contents are heated to boiling and then acetylbutyrolactone and hydrochloric acid are fed separately into the flask in mol. for mol. proportions. The condensed distillate flows into the separator where the acetylpropyl chloride separates as the bottom layer and is continuously withdrawn. The acetylbutyrolactone may be prepared by reacting ethylene oxide with ethyl acetoacetate as described in Specification 601,802. Specification 558,286 also is referred to. |
