发明名称 |
COMPOSITIONS FOR MANIPULATING PIM-1 ACTIVITY IN CARDIAC CELLS |
摘要 |
The invention provides compositions (e.g., pharmaceutical compositions) comprising nucleic acids encoding the serine/threonine kinase PIM-1, and methods for making and using them; including methods for inducing cellular proliferation, and protecting cardiac cells from hypoxia and cellular apoptosis. The invention provides compositions (e.g., pharmaceutical compositions) comprising nucleic acids encoding PIM-1, and methods for enhancing the regenerative potential of stem cells in the heart. |
申请公布号 |
EP2209889(B1) |
申请公布日期 |
2016.07.20 |
申请号 |
EP20080850768 |
申请日期 |
2008.11.14 |
申请人 |
SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION |
发明人 |
MURASKI, JOHN, A., JR.;SUSSMAN, MARK, A. |
分类号 |
C12N5/0775 |
主分类号 |
C12N5/0775 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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