发明名称 Substituted carbamoylmethoxyacetic acid derivatives as novel NEP inhibitors
摘要 The present invention provides a compound of formula I; or a pharmaceutically acceptable salt thereof, wherein R 1 , R 2 , R 3 , R 4 , R 6 , A 1 , A 2 , X 1 , sand m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
申请公布号 EP2735561(B1) 申请公布日期 2016.07.20
申请号 EP20140155848 申请日期 2010.11.18
申请人 NOVARTIS AG 发明人 IWAKI, YUKI;KAWANAMI, TOSHIO;KSANDER, GARY MICHAEL;MOGI, MUNETO
分类号 C07D231/40;A61K31/41;A61K31/415;A61K31/42;A61P7/10;C07D257/06;C07D261/14 主分类号 C07D231/40
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