发明名称 METHOD FOR PREVENTION OF HAEMATOGENOUS METASTASIS IN SURGICAL TREATMENT OF PATIENTS WITH LOCALLY ADVANCED CERVICAL CANCER
摘要 FIELD: medicine.SUBSTANCE: combined surgical method of treating with intraoperative intra-arterial chemotherapy. During surgical intervention Piver type III at stage of crossing infundibular-pelvic and round uterine ligaments on both sides, retroperitoneal space iliac regions are opened. Exposing and taking on inner iliac artery ligature. On both sides of inner iliac artery is ligated below origin of common iliac artery two ligatures and simultaneously in both distal sections of tied vessels, taken on additional ligatures, bolus slowly with underlying excessive hydration and forced diuresis 25 mg of cisplatin is introduced. After removal of needles provisional ligatures are fastened to prevent reverse blood flow from arteries. Exposure of transport cytostatic is 20 minutes, then surgical intervention is performed at common plan.EFFECT: method improves general and free survival, prevents haematogenous metastasis tumour during a surgical intervention, reduces number of loco-regional recurrences, reduces rate of developing side toxic responses chemotherapy without increasing number of perioperative complications.1 cl, 1 ex
申请公布号 RU2591612(C1) 申请公布日期 2016.07.20
申请号 RU20150127610 申请日期 2015.07.08
申请人 FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE UCHREZHDENIE "ROSTOVSKIJ NAUCHNO-ISSLEDOVATELSKIJ ONKOLOGICHESKIJ INSTITUT" MINISTERSTVA ZDRAVOOKHRANENIYA ROSSIJSKOJ FEDERATSII 发明人 MOISEENKO TATYANA IVANOVNA;MENSHENINA ANNA PETROVNA;FRANTSIYANTS ELENA MIKHAJLOVNA;NEPOMNYASHSHAYA EVGENIYA MARKOVNA;NAZARLIEVA NELLI ALBERTOVNA
分类号 A61B17/42;A61K31/282;A61P35/00 主分类号 A61B17/42
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