发明名称 機能的分子の可逆的共有結合
摘要 The present invention relates to the use of a compound of formula (Ia) as a reagent for linking a compound of formula R 1 -H which comprises a first functional moiety of formula F 1 to a second functional moiety of formula F 2 wherein X, X', Y, R 1 , R 2 , R 3 , R 3 ', F 1 and F 2 are as defined herein. The present invention also provides related processes and products. The present invention is useful for creating functional conjugate compounds, and specifically conjugates in which at least one of the constituent molecules carries a thiol group.
申请公布号 JP5954789(B2) 申请公布日期 2016.07.20
申请号 JP20120524272 申请日期 2010.08.09
申请人 ユーシーエル ビジネス パブリック リミテッド カンパニー 发明人 スミス、マーク;キャディック、ステファン;ベイカー、ジェイムズ;チュダサマ、ヴィジェイ
分类号 A61K47/48;A61K38/43;A61K39/395;A61K45/00;A61K51/00;C07D207/444;C07D209/52;C07K14/655 主分类号 A61K47/48
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