发明名称 |
BIOMARKERS FOR PSORIASIS TREATMENT RESPONSE |
摘要 |
Single nucleotide polymorphisms (SNPs) are provided that correlate with responsiveness of psoriasis patients to treatment with a therapeutic antibody that specifically binds to the p19 subunit of IL-23. The SNPs are used as biomarkers to prospectively selecting psoriasis patients likely to benefit from treatment with antagonists of IL-23, such as an antibody that specifically binds to the p19 subunit of IL-23. |
申请公布号 |
EP2935626(A4) |
申请公布日期 |
2016.07.20 |
申请号 |
EP20130864159 |
申请日期 |
2013.12.19 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
MCELWEE, JOSHUA;MOGG, ROBIN;MEHROTRA, DEVAN |
分类号 |
C12Q1/68;A61P17/06 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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