| 摘要 |
FIELD: pharmaceutics.SUBSTANCE: invention is a topical composition in form of an aerosol powder for treatment and/or prevention of infection of skin lesions containing silver sulfadiazine and at least one silicate, characterised in that said composition contains silver sulfadiazine in an amount from 0.1 to 5 wt% relative to total weight of composition, at least one silicate in an amount of 92 to 99 wt% relative to total weight of composition, and a pharmaceutically acceptable excipient - balance, wherein pharmaceutically acceptable excipient has a particle size less than 13 mcm, and/or 90 % of particles have a size of from 5 to 10 mcm, and/or 50 % of particles are smaller than 4 mcm and wherein silicate is selected from hydrated magnesium silicate, aluminum silicate, calcium silicate or mixtures thereof.EFFECT: invention provides intensified therapeutic effectiveness.11 cl, 2 dwg, 2 ex |
