发明名称 OPHTHALMIC SOLUTION
摘要 Provided is an ophthalmic solution of which preservative component, hexamethylene biguanide, contained therein is inhibited from being adsorbed on soft contact lenses and eye droppers. The ophthalmic solution contains, at a specific ratio, (A) hydroxypropyl methylcellulose having 28.0 to 30.0 mass% methoxy groups and 7.0 to 12.0 mass% hydroxypropoxy groups, both with respect to the total amount of the hydroxypropyl methylcellulose, at a methoxy group/hydroxypropoxy group ratio of 2.5 to 4.0 by mass, wherein a 2 mass% aqueous solution of the hydroxypropyl methylcellulose at 20 °C has a viscosity of 50 to 4000 mPa·s; (B) sodium chloride or potassium chloride; (C) hexamethylene biguanide or a salt thereof; (D) 2-methacryloyloxyethyl phosphorylcholine/butyl methacrylate copolymer; and (E) water.
申请公布号 EP3040085(A1) 申请公布日期 2016.07.06
申请号 EP20140839905 申请日期 2014.08.05
申请人 NOF CORPORATION 发明人 SAKURAI, SHUNSUKE;MIYAMOTO, KOJI;TAKADA, YOHEI;SHIMAMURA, YOSHIHISA;MARUHASHI, MAO;SAKAMOTO, NOBUYUKI
分类号 A61K9/08;A61K47/04;A61K47/32;A61K47/34;A61K47/38 主分类号 A61K9/08
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