发明名称 |
SUBSTITUTED UREA DEPSIPEPTIDE ANALOGS AS ACTIVATORS OF THE CLPP ENDOPEPTIDASE |
摘要 |
In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
申请公布号 |
EP3038640(A1) |
申请公布日期 |
2016.07.06 |
申请号 |
EP20140841099 |
申请日期 |
2014.08.30 |
申请人 |
ST. JUDE CHILDREN'S RESEARCH HOSPITAL |
发明人 |
LEE, RICHARD E.;ZHAO, YING;GRIFFITH, ELIZABETH;ZHENG, ZHONG;SINGH, AMAN P. |
分类号 |
A61K38/15;A61P31/00;C07K11/02 |
主分类号 |
A61K38/15 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|