CADHERIN-11 ANTAGONIST FOR THE TREATMENT OF FIBROSIS
摘要
Methods of treating a subject having fibrosis or at risk of developing fibrosis by administering a Cadherin-11 (CDH11 ) antagonist are provided. The treatment may be administered to subjects with dermal or non-dermal fibrosis, including lung, liver or kidney fibrosis or idiopathic pulmonary fibrosis. Methods of assessing the levels of CDH11 in a subject and determining fibrosis or risk of developing fibrosis are also provided.
申请公布号
EP2566967(B1)
申请公布日期
2016.07.06
申请号
EP20110778233
申请日期
2011.05.04
申请人
THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人
AGARWAL, SANDEEP, K.;SCHNEIDER, DANIEL, J.;BRENNER, MICHAEL, B.