发明名称 |
NEW USE |
摘要 |
The present invention relates to methods and pharmaceutical compositions for renal protection in a mammal in need thereof, such as a mammal having a disease manifested by atrial enlargement and/or remodeling or suffering from hypertension or heart failure or being prone to suffering from hypertension and/or heart failure, comprising administration of a therapeutically effective amount, or a prophylactically effective amount, of an Angiotensin Receptor Neprilysin inhibitor (ARNi) or of a combination of an Angiotensin Receptor Blocker (ARB) with a Neutral Endopeptidase inhibitor (NEPi) or with a NEPi pro-drug to said mammal. |
申请公布号 |
EP3038653(A1) |
申请公布日期 |
2016.07.06 |
申请号 |
EP20130759384 |
申请日期 |
2013.08.26 |
申请人 |
NOVARTIS AG |
发明人 |
BRANSFORD, Toni Lynne;BURKEY, Bryan;LANGENICKEL, Thomas;SHI, Victor Chengwei;LEFKOWITZ, Martin |
分类号 |
A61K45/06;A61K31/194;A61K31/197;A61K31/216;A61P9/10;A61P9/12 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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