发明名称 |
USE OF MICROVESICLES IN DIAGNOSIS, PROGNOSIS, AND TREATMENT OF MEDICAL DISEASES AND CONDITIONS |
摘要 |
The present invention discloses methods for diagnosing or prognosing a disease or medical condition in a subject by detecting the presence or absence of BRAF mutant nucleic acids from nucleic acids extracted from microvesicles from a biological sample. The present invention also discloses methods for assessing the responsiveness or determining a treatment regimen for a subject in need thereof by detecting the presence or absence of BRAF mutant nucleic acids from nucleic acids extracted from microvesicles from a biological sample. Methods for isolating microvesicles and extracting DNA and/or RNA from the microvesicles are also described. |
申请公布号 |
EP2903597(A4) |
申请公布日期 |
2016.07.06 |
申请号 |
EP20130844278 |
申请日期 |
2013.10.03 |
申请人 |
EXOSOME DIAGNOSTICS INC. |
发明人 |
COMPER, WAYNE;RAMACHANDRAN, APARNA;YAN, HAOHENG;RUSSO, LEILEATA, M.;SKOG, JOHAN KARL OLOV |
分类号 |
A61K9/00;A61M5/00;C12Q1/68 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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