发明名称 |
Use of mullerian inhibiting substance (MIS) proteins for contraception and ovarian reserve preservation |
摘要 |
One aspect of the invention provides a method of contraception by administering to a female subject a composition comprising Mullerian inhibiting substance (MIS). The MIS can be produced endogenously in the subject by a vector, where the vector comprises a polynucletide encoding a recombinant MIS protein. In some embodiments, the contraception is permanent and only requires administration of the composition once. Another aspect of the invention relates to a method of preserving an ovarian reserve, the method comprising administering to a female subject a composition comprising MIS or an inducible vector that comprises a polynucleotide encoding a recombinant MIS protein. |
申请公布号 |
AU2014362307(A1) |
申请公布日期 |
2016.06.30 |
申请号 |
AU20140362307 |
申请日期 |
2014.12.11 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
DONAHOE, PATRICIA K.;PEPIN, DAVID |
分类号 |
A61K38/22;A61K48/00;C12N15/86 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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