HUMAN TOLL-LIKE RECEPTOR INHIBITORS AND METHODS OF USE THEREOF TOLL
摘要
Provided herein are human Toll-like receptor (TLR)-inhibitors and methods for use in individuals having an autoimmune disease or an inflammatory disorder. The TLR inhibitors of the present disclosure are polynucleotides comprising an inhibitory motif for one or more of TLR7, TLR8 and TLR9.
申请公布号
HK1213290(A1)
申请公布日期
2016.06.30
申请号
HK20160101143
申请日期
2016.02.01
申请人
DYNAVAX TECHNOLOGIES CORPORATION
发明人
GUIDUCCI, Cristiana C;FEARON, Karen, L. KL;BARRAT, Franck F