发明名称 PYRAZOLOQUINOLINE COMPOUND
摘要 Provided is a compound of general formula (I) or a pharmaceutically acceptable salt thereof, which has a PDE9-inhibiting action and is useful as an active ingredient for an agent for treating and/or preventing storage dysfunction, voiding dysfunction, bladder/urethral diseases, and the like. The inventors of the present invention have investigated a compound which has a PDE9-inhibiting action and is useful as an active ingredient for an agent for treating and/or preventing storage dysfunction, voiding dysfunction, bladder/urethral diseases, and the like, and thus, have found that a pyrazoloquinoline compound has a PDE9-inhibiting action, thereby completing the present invention. The pyrazoloquinoline compound of the present invention has a PDE9-inhibiting action and can be used as an agent for preventing and/or treating storage dysfunction, voiding dysfunction, bladder/urethral diseases, and the like. The present invention also relates to a pharmaceutical composition inhibiting PDE9 activity, comprising the compound of formula (I) and a pharmaceutical acceptable excipientwherein radicals are defined in the claims.
申请公布号 EA023493(B1) 申请公布日期 2016.06.30
申请号 EA20130090353 申请日期 2011.09.07
申请人 ASTELLAS PHARMA INC. 发明人 KAIZAWA HIROYUKI;YAMAMOTO HIROFUMI;KAMIJO KAZUNORI;SUGITA MARI;SEO RYUSHI;YAMAMOTO SATOSHI;UKAI ATSUSHI
分类号 C07D471/04;A61K31/4738;A61K31/496;A61K31/4985;A61K31/5377;A61P13/00;A61P13/02;C07D519/00 主分类号 C07D471/04
代理机构 代理人
主权项
地址