REMOVAL OF MICROORGANISMS FROM CELL CULTURE MEDIA BY MICROPOROUS MEMBRANES

摘要

A microporous filtration membrane and methods are provided for removing viral contaminants from a chemically defined cell culture medium. The surface of the membranes is modified with a compositions comprising apolymer with randomly arrnged and crosslinked diacetone acrylamide and polyethylene glycol diacrylate to render the membrane resistant to or exhibiting reduced fouling by one or more components in a chemically defined cell culture medium.