发明名称 AMINOMETHYL BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
摘要 The present invention is directed to aminomethyl compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
申请公布号 EP1855679(B1) 申请公布日期 2016.06.29
申请号 EP20060718443 申请日期 2006.01.13
申请人 MERCK SHARP & DOHME CORP. 发明人 COBURN, CRAIG, A.;NANTERMET, PHILIPPE, G.;RAJAPAKSE, HEMAKA, A.;SELNICK, HAROLD, G.;STAUFFER, SHAUN, R.
分类号 A61K31/4745;A61P25/28;C07D271/06;C07D271/10;C07D413/06 主分类号 A61K31/4745
代理机构 代理人
主权项
地址