Medical Devices for Delivering a Bioactive to a Point of Treatment and Methods of Making Medical Devices

摘要

Methods of making medical devices are described. A method of making a medical device for delivering a bioactive includes preparing a suitable solution comprising the bioactive; placing a vessel containing the solution over a substrate comprising a biocompatible foam and defining open cells; initiating flow of the solution from the vessel and toward the substrate such that the solution exits the vessel and contacts the substrate; and maintaining flow of the solution for an amount of time sufficient to achieve a desired volume of the solution within the substrate. Medical devices made by the methods are also described.

主权项

1. A method of making a medical device for delivering a bioactive, said method comprising:
preparing a suitable water-based solution comprising said bioactive; placing a vessel containing the solution over a substrate comprising a biocompatible foam formed of an expanded natural material and defining a plurality of cells; initiating flow of the solution from the vessel and toward the substrate such that the solution exits the vessel and contacts the substrate; massaging the substrate to facilitate entry of the solution into the substrate; and maintaining flow of the solution for an amount of time sufficient to achieve a desired volume of the solution within the substrate.