发明名称 |
ENGINEERED GAMMA DELTA T-CELLS |
摘要 |
The present invention relates to engineered γδ T-cell(s) and methods for using the same as a therapeutic with a potent and selective ability to target an antigen of choice. Engineered γδ T-cells of the disclosure are useful in the treatment of various cancers, infectious diseases, and immune disorders. Also disclosed are methods for expanding engineered and non-engineered γδ T-cell(s) populations to therapeutically useful quantities. An engineered γδ T-cell of the disclosure can be a universal donor, and can be administered to a subject with any MHC haplotype. |
申请公布号 |
US2016175358(A1) |
申请公布日期 |
2016.06.23 |
申请号 |
US201514944106 |
申请日期 |
2015.11.17 |
申请人 |
Adicet Bio, Inc. |
发明人 |
Jakobovits Aya;Foord Orit;Lin Andy An-deh;Santaguida Marianne Theresa |
分类号 |
A61K35/17;C07K14/705;C12N5/0783 |
主分类号 |
A61K35/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
South San Francisco CA US |