METHODS AND SYSTEMS FOR COHERENT RAMAN SCATTERING

摘要

Systems and methods employing Coherent Raman Scattering (CRS), e.g., Coherent anti-Stokes Raman Spectroscopy (CARS) and/or Stimulated Raman Scattering (SRS) are provided. Systems and methods for performing flow cytometry, imaging and sensing using low-resolution CRS are also provided.

主权项

1. A detection system comprising:
a fiber laser system configured to provide; a first train of pulses at a laser repetition rate R1 and having a first center optical frequency ω1 and an optical bandwidth of Δω1; a second train of pulses at a laser repetition rate R2 and having a second center optical frequency ω2 and an optical bandwidth of Δω2, wherein the second train of pulses is synchronized with the first train of pulses; focusing optics configured to focus spectral elements from the first and the second trains of pulses toward at least one overlapping focal volume, wherein the at least one overlapping focal volume has at least two dimensions that are larger than 3 μm; and a detector system configured to detect a non-linear optical signal from the at least one overlapping focal volume.