A murine cell whose genome comprises at least two low affinity human FcyR a-chain genes that replace the endogenous low affinity FcyR a-chain genes, wherein the cell comprises a functional endogenous FcR y-chain and functionally expresses the at least two low affinity human FcyR a-chain genes.
申请公布号
AU2014210646(B2)
申请公布日期
2016.06.23
申请号
AU20140210646
申请日期
2014.08.08
申请人
REGENERON PHARMACEUTICALS, INC.
发明人
MACDONALD, LYNN;TU, NAXIN;GURER, CAGAN;STEVENS, SEAN;MURPHY, ANDREW J.
