METHOD FOR PRODUCING PEGYLATED SILICA NANOPARTICLES AS CARRIERS OF HYDROPHOBIC PHARMACEUTICAL DRUGS, THUS OBTAINED NANOPARTICLES AND USES THEREOF

摘要

The present invention relates to a method for producing PEGylated silica nanoparticles as carriers of hydrophobic pharmaceutical drugs, to the silica nanoparticles obtained by this or other methods, and to the use thereof for the treatment of cancer. The nanoparticles effectively retain the pharmaceutical drug inside them, preventing the premature release of the drug in the external medium during intraveinous transport, reducing the collateral effects associated with chemotherapy and the dose concentration required for an antitumoral treatment.