发明名称 |
Crystalline forms of antiviral Sofosbuvir analogues |
摘要 |
Crystalline solid forms of the anti-HCV compound (S)-isopropyl 2-((S)-(((2R,3R,4R,5R)- 5-(2,4-dioxo-3,4-dihydropyrimidin-l(2H)-yl)-4-fluoro-3-hydroxy-4- methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate (Compound I) are described. Also provided are processes of making and methods of using the crystalline forms. |
申请公布号 |
AU2014370299(A1) |
申请公布日期 |
2016.06.23 |
申请号 |
AU20140370299 |
申请日期 |
2014.12.08 |
申请人 |
GILEAD PHARMASSET LLC |
发明人 |
CASTEEL, MELISSA JEAN;DASHNER, KATHLEEN;JUNG, HYUK-JUN;SEO, MUN SIK;SHI, BING;WANG, FANG;ZIA, VAHID |
分类号 |
A61K31/7072;A61P31/18;C07F9/6558;C07H19/10 |
主分类号 |
A61K31/7072 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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