发明名称 |
HUMAN ANTI-PD-1, PD-L1, AND PD-L2 ANTIBODIES AND USES THEREOF |
摘要 |
The present invention is based, in part, on the identification of novel human anti-PD-1, PD-L1, and PD-L2 antibodies. Accordingly, the invention relates to compositions and methods for diagnosing, prognosing, and treating conditions that would benefit from modulating PD-1, PD-L1, and/or PD-L2 activity (e.g., persistent infectious diseases, autoimmune diseases, asthma, transplant rejection, inflammatory disorders and tumors) using the novel human anti-PD-1, PD-L1, and PD-L2 antibodies described herein. |
申请公布号 |
EP2342226(B1) |
申请公布日期 |
2016.06.22 |
申请号 |
EP20090816950 |
申请日期 |
2009.09.25 |
申请人 |
DANA-FARBER CANCER INSTITUTE, INC.;EMORY UNIVERSITY |
发明人 |
FREEMAN, GORDON, J.;AHMED, RAFI;JONES, TIMOTHY, D.;CARR, FRANCIS, J.;GREGSON, JAMES, P. |
分类号 |
C07K16/28;A61K39/395;A61P31/00;A61P35/00 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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