| 摘要 |
Helicobacter pylori, one of the most common human pathogens, is associated with the development of human chronic gastritis, peptic ulcers and gastric cancer. The invention relates to a α1,6-glucan-containing Helicobacter pylori compound comprising the structure of Formula I: wherein R is a α-DDHep-3-α-L-Fuc-3-&bgr;-GlcNAc trisaccharide substituted with an α1,6-glucan linked to an α1,3-DD-heptan, and wherein the last DD-Hep residue of α1,3-DD-heptan is capped with &bgr;-GlcNAc residue. Compositions comprising the compound, uses of the compound, and antibodies raised against the compound are also described. |
