| 发明名称 |
MULTIMERIC PROTEINS ABLE TO INDUCE AN ANTIBODY RESPONSE AGAINST THE BETA-AMYLOID AND USE THEREOF |
| 摘要 |
The present invention relates to the fields of molecular biology, immunology and medicine. Peptide sequences that belong to the beta amyloid peptide are exposed on the surface of a multimeric structure derived from the E2 component of alpha keto acid dehydrogenase. The molecules are useful for the production of vaccines for the treatment and/or prevention of Alzheimer's disease. |
| 申请公布号 |
EP2238160(B1) |
申请公布日期 |
2016.06.22 |
| 申请号 |
EP20090705591 |
申请日期 |
2009.01.27 |
| 申请人 |
CONSIGLIO NAZIONALE DELLE RICERCHE |
发明人 |
PRISCO, ANTONELLA;DE BERARDINIS, PIERGIUSEPPE;DE FALCO, DIANA;CAIVANO, ANTONELLA |
| 分类号 |
C07K14/47;A61K39/385;C12N15/62 |
主分类号 |
C07K14/47 |
| 代理机构 |
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