发明名称 |
TISSUE ENGINEERED MODELS OF CANCERS |
摘要 |
A 3D decellularized bone scaffold seeded with cancer cells, such as prostate cancer cells or Ewing's sarcoma is provided. It provides platform technology for controllable, quantitative, long-term studies of tissue-engineered tumors, including prostate cancer and Ewing's sarcoma. The scaffold can be used with cancer cell lines to identify therapeutic targets to slow, stop, and reverse tumor growth and progression as well as to predict the efficacy of potential therapeutics. |
申请公布号 |
US2016168542(A1) |
申请公布日期 |
2016.06.16 |
申请号 |
US201414908870 |
申请日期 |
2014.08.01 |
申请人 |
THE TRUSTEES OF COLUMBIA UNICERSITY IN THE CITY OF NEW YORK |
发明人 |
Villasante Aranzazu;Vunjak-Novakovic Gordana |
分类号 |
C12N5/09;C12M1/00;C12M1/12;B01J19/00;C12M3/00 |
主分类号 |
C12N5/09 |
代理机构 |
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代理人 |
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主权项 |
1. A three-dimensional cancer model, the model comprising:
a decellularized bone scaffold; and a plurality of cells arrayed on the scaffold. |
地址 |
New York NY US |