发明名称 |
METHODS OF TREATING PRURITIC CONDITIONS MEDIATED THROUGH HISTAMINE H-4 RECEPTORS |
摘要 |
The methods disclosed herein relate to the treatment of histamine H-4—related pruritus, by administering a histamine H-4 receptor inverse agonist that selectively accumulates at the biophases of the disorders, specifically RS-norketotifen or a pharmaceutically acceptable salt thereof. Potentiated antipruritic activity by simultaneous inhibition of histamine H-1 receptors and histamine H-4 receptors are described. |
申请公布号 |
EP3030238(A1) |
申请公布日期 |
2016.06.15 |
申请号 |
EP20140750951 |
申请日期 |
2014.07.31 |
申请人 |
BRIDGE PHARMA, INC. |
发明人 |
ABERG, A. K. GUNNAR;CIOFALO, VINCENT B. |
分类号 |
A61K31/4535;A61P17/04 |
主分类号 |
A61K31/4535 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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