| 摘要 |
THE INVENTION PROVIDES COMPOUNDS OF FORMULA 1 OR A PHARMACEUTICALLY ACCEPTABLE SALT OR ESTER THEREOFWHEREIN THE SYMBOLS HAVE MEANINGS AS DEFINED, WHICH ARE INHIBITORS OF CATHEPSIN K AND FIND USE PHARMACEUTICALLY FOR TREATMENT OF DISEASES AND MEDICAL CONDITIONS IN WHICH CATHEPSIN K IS IMPLICATED, E.G. VARIOUS DISORDERS INCLUDING INFLAMMATION, RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPOROSIS AND TUMORS. |
