摘要 |
The present invention relates to a therapeutic compound comprising: - an agent that inhibits the activity of at least one gene selected from the group consisting of MEOX2, MAF, SIX2 and homologues thereof having at least 50% identity with said genes and/or - an agent that enhances the activity of at least one gene selected from the group consisting of CREB5, E2F1, EGR2, HIC1, IRF7, JUN, MYC, SRF, STAT4, TCF4, FOXS1, GLI1, SOX9 and homologues thereof having at least 50% identity with said gene for use in the treatment of wounds, preferably chronic wounds. |
申请人 |
URGO RECHERCHE INNOVATION ET DÉVELOPPEMENT;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);UNIVERSITÉ PARIS DIDEROT - PARIS 7;INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE);ECOLE NORMALE SUPÉRIEURE |
发明人 |
DUGAST-DARZACQ, CLAIRE;NOIZET, MAÏTÉ;DARZACQ, XAVIER;SPILUTTINI HÉBERT, BÉATRICE |