发明名称 |
COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES |
摘要 |
The present invention relates to compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in need thereof an effective amount of a compound defined herein (including those compounds set forth in Tables 1-2 or encompassed by formulas I-IV) or compositions thereof, thereby treating the disease. The present invention particularly, relates to a method of treating diarrhea and polycystic kidney disease. |
申请公布号 |
EP2278879(B1) |
申请公布日期 |
2016.06.15 |
申请号 |
EP20090734016 |
申请日期 |
2009.04.20 |
申请人 |
PATH DRUG SOLUTIONS |
发明人 |
JONES, GRAHAM, PETER;DOYLE, KEVIN, JAMES |
分类号 |
C07D271/06;A61K31/4245;C07D271/04;C07D413/06;C07D413/12;C07D413/14 |
主分类号 |
C07D271/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|