发明名称 SITE-DIRECTED CRISPR/RECOMBINASE COMPOSITIONS AND METHODS OF INTEGRATING TRANSGENES
摘要 Disclosed herein are targeted chimeric polypeptides, compositions thereof, expression vectors, and methods of use thereof, for the generation of transgenic cells, tissues, plants, and animals. The compositions, vectors, and methods of the present invention are also useful in gene therapy and cell therapy techniques. The chimeric polypeptide includes a CRISPR-Cas domain and a recombinase domain.
申请公布号 WO2016090385(A1) 申请公布日期 2016.06.09
申请号 WO2015US64352 申请日期 2015.12.07
申请人 APPLIED STEMCELL, INC. 发明人 TSAI, RUBY, YANRU
分类号 C12N9/22;C12N15/113;C12N15/52;C12N15/85 主分类号 C12N9/22
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