发明名称 |
METHOD FOR MANUFACTURING IMMUNOCYTE-CONTAINING COMPOSITION, AND CANCER-TREATING COMPOSITION |
摘要 |
To provide a method in which mononuclear cells are differentiated into a good balance of NK cells, NKT cells, and T cells, and said cells are made to proliferate. The present invention provides a method for manufacturing an immune cell-containing composition, said method including the following steps: a first step in which mononuclear cells are cultured in a medium containing anti-CD16 monoclonal antibodies and either IL-2 and/or IL-15; and a second step, after the first step, in which culturing is performed under conditions that make the mononuclear cells preferentially differentiate into cytotoxic T cells. This method may also include a third step, after the second step, in which culturing is performed in a medium containing anti-CD16 monoclonal antibodies and either IL-2 and/or IL-15. |
申请公布号 |
EP2947144(A4) |
申请公布日期 |
2016.06.08 |
申请号 |
EP20140740451 |
申请日期 |
2014.01.14 |
申请人 |
ABE, HIROYUKI;YUSA, SEIICHI |
发明人 |
ABE, HIROYUKI;YUSA, SEIICHI |
分类号 |
C12N5/0783;A61K35/14;A61P35/00;C12N5/078 |
主分类号 |
C12N5/0783 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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