发明名称 |
POLYMERIC COMPOUND HAVING CAMPTOTHECIN COMPOUND AND ANTI-CANCER EFFECT ENHANCER BOUND THERETO, AND USE OF SAME |
摘要 |
The purpose of the present invention is to provide a polymeric compound in which a camptothecin compound and an anti-cancer effect enhancer, particularly a PARP inhibitor, are bound to a single molecule, whereby it becomes possible to reduce the toxicity to normal cells and deliver and release the two components to an affected area with high efficiency to thereby improve the pharmacological efficacy of the two components. Provided is a polymeric compound represented by general formula (1). |
申请公布号 |
EP2918292(A4) |
申请公布日期 |
2016.06.08 |
申请号 |
EP20130853624 |
申请日期 |
2013.10.31 |
申请人 |
NIPPON KAYAKU KABUSHIKI KAISHA |
发明人 |
YAMAMOTO, KEIICHIRO;OKAZAKI, MANAMI |
分类号 |
A61K47/48;A61K31/4184;A61K31/4745;A61K31/55;A61K31/551;A61K47/34;A61P35/00;A61P43/00 |
主分类号 |
A61K47/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|