| 发明名称 |
BICYCLIC UREAS AND THIADIAZOLIDINE-1,1-DIOXIDES AS CETP INHIBITORS |
| 摘要 |
Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, wherein X is —C(═O) or —S(O)2—, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. |
| 申请公布号 |
EP3027619(A2) |
申请公布日期 |
2016.06.08 |
| 申请号 |
EP20140832256 |
申请日期 |
2014.07.28 |
| 申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
LIU, JIAN;SHAO, PENGCHENG PATRICK;KRIKORIAN, ARTO, D.;VACHAL, PETR |
| 分类号 |
C07D487/04;A61K31/4188;A61K31/433;A61K31/4436;A61K31/4439;A61P3/06;A61P9/10;A61P9/12;C07D513/04 |
主分类号 |
C07D487/04 |
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