| 摘要 |
A ring-fused heterocyclic derivative represented by the following general formula (I) or a pharmaceutically acceptable salt thereof having a T-type calcium channel regulatory effect and useful as a pruritus therapeutic and/or preventive agent, and the like are provided. In the general formula (I), R 1 represents optionally substituted lower alkyl, and the like; R 2 represents an optionally substituted cycloalkyl, and the like; Q represents a hydrogen atom, and the like; R 3 represents -C(=O)NR 8 R 9 (wherein R 8 and R 9 may be the same or different, and each represents a hydrogen atom, and the like), and the like; L 1 represents -CR 11A R 11B - (wherein R 11A and R 11B may be the same or different, and each represents a hydrogen atom, and the like), and the like; and W 1 and W 2 may be the same or different, and each represents C-R 12 (wherein R 12 represents a hydrogen atom, and the like), and the like. |
