セルトリ細胞のマイクロカプセル化方法、得られるマイクロカプセルおよび１型糖尿病の予防および治療のためのその用途

摘要

An apparatus for production of microcapsules includes a volumetric pump configured to deliver a polysaccaridic suspension through a catching tube. A needle-type element is configured to receive the suspension through the catching tube, and the needle-type element has a button hole opening in a lateral wall thereof and an output hole that outputs the suspension. The button hole opening receives a pressure fluid current. A pressure regulator is coupled to the button hole opening to regulate the pressure fluid current to interrupt a suspension flow and obtain microdroplets of homogeneous size exiting the output hole. The microdroplets are received in a receiving container in a solution including divalent cations or polycationic substances to form a gel such that homogeneous microcapsules are formed.