主权项 |
1. Compound of the formulain which
n represents the number 1 or 2, A represents —N(R2)— or —CH2—,
whereinR2 represents hydrogen or C1-C4-alkyl, R1 represents a group of the formula where * is the point of attachment to the oxopyridine ring,R6 represents bromine, chlorine, fluorine, methyl, difluoromethyl, trifluoromethyl, methoxy, difluoromethoxy or trifluoromethoxy,R7 represents hydrogen, bromine, chlorine, fluorine, cyano, nitro, hydroxy, methyl, difluoromethyl, trifluoromethyl, methoxy, ethoxy, difluoromethoxy, trifluoromethoxy, ethynyl, 3,3,3-trifluoroprop-1-yn-1-yl or cyclopropyl,R8 represents hydrogen, chlorine or fluorine, R3 represents hydrogen, R4 represents hydrogen, R5 represents a group of the formula where # is the attachment site to the nitrogen atom,R9 represents hydroxycarbonyl or 5-membered heterocyclyl,
where heterocyclyl may be substituted by 1 to 2 substituents independently of one another selected from the group consisting of oxo, hydroxy, thioxo, sulphanyl, methyl, difluoromethyl, trifluoromethyl, 2-hydroxycarbonyl-1, 1,2,2-tetrafluoroethyl and 2-methoxycarbonyl-1,1,2,2-tetrafluoroethyl,
where methyl may be substituted by a methoxy substituent,R10 represents hydrogen, chlorine, fluorine or methyl,R11 and R12 together with the carbon atoms to which they are bonded form a 5-membered heterocycle,
where the heterocycle may be substituted by 1 to 2 substituents independently of one another selected from the group consisting of oxo, chlorine, hydroxy, hydroxycarbonyl, methyl, difluoromethyl, trifluoromethyl, 1,1,2,2,2-pentafluoroethyl, 2-hydroxycarbonyl-1,1,2,2-tetrafluoroethyl and 2-methoxycarbonyl-1,1,2,2-tetrafluoroethyl,R13 represents hydrogen, chlorine, fluorine, methyl or methoxy,or one of the salts thereof. |